When tissue is damages platelets are among the first cells attracted to the area. Platelets become sticky in the presence of tissue damage or damage to blood vessels. Once platelets stick they release chemicals that support tissue regeneration. These factors are listed below:
- platelet-derived growth factor
- transforming growth factor beta
- fibroblast growth factor
- insulin-like growth factor 1
- insulin-like growth factor 2
- vascular endothelial growth factor
- epidermal growth factor
- Interleukin 8
- keratinocyte growth factor
- connective tissue growth factor
Platelet Rich Plasma (PRP) is created by collecting a blood sample from your pet into a specially prepared tube then using a special centrifuge to concentrate the platelets.
The platelets may then be stimulated to de-granulate with the use of chemicals.
The PRP is then injected into areas needing regeneration. This might be into an arthritic joint, or a joint undergoing surgery, into a ligament or just IV.
PRP may be used along with Stem Cell Therapy to promote stem cell activity.